Recent additions may not be included but will usually appear in 24 hrs or less.
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The inhibitory effect of polyphenols on human gut microbiota. β
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society (J Physiol Pharmacol ) Vol: 63 Issue 5 Pages: 497-503 Pub: 2012 Oct Epub: Authors Duda-Chodak A , |
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<i>Bacteroides thetaiotaomicron</i> Starch Utilization Promotes Quercetin Degradation and Butyrate Production by <i>Eubacterium ramulus</i>. β
Go to Publication β
Frontiers in microbiology (Front Microbiol ) Vol: 10 Issue Pages: 1145 Pub: 2019 Epub: 2019 May 29 Authors Rodriguez-Castaño GP , Dorris MR , Liu X , Bolling BW , Acosta-Gonzalez A , Rey FE , |
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Dietary Quercetin Increases Colonic Microbial Diversity and Attenuates Colitis Severity in <i>Citrobacter rodentium</i>-Infected Mice. β
Go to Publication β
Frontiers in microbiology (Front Microbiol ) Vol: 10 Issue Pages: 1092 Pub: 2019 Epub: 2019 May 16 Authors Lin R , Piao M , Song Y , |
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Dietary Quercetin Increases Colonic Microbial Diversity and Attenuates Colitis Severity in <i>Citrobacter rodentium</i>-Infected Mice. β
Go to Publication β
Frontiers in microbiology (Front Microbiol ) Vol: 10 Issue Pages: 1092 Pub: 2019 Epub: 2019 May 16 Authors Lin R , Piao M , Song Y , |
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Dietary Quercetin Increases Colonic Microbial Diversity and Attenuates Colitis Severity in <i>Citrobacter rodentium</i>-Infected Mice. β
Go to Publication β
Frontiers in microbiology (Front Microbiol ) Vol: 10 Issue Pages: 1092 Pub: 2019 Epub: 2019 May 16 Authors Lin R , Piao M , Song Y , |
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Dietary Quercetin Increases Colonic Microbial Diversity and Attenuates Colitis Severity in <i>Citrobacter rodentium</i>-Infected Mice. β
Go to Publication β
Frontiers in microbiology (Front Microbiol ) Vol: 10 Issue Pages: 1092 Pub: 2019 Epub: 2019 May 16 Authors Lin R , Piao M , Song Y , |
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Effect of Quercetin on Lipids Metabolism Through Modulating the Gut Microbial and AMPK/PPAR Signaling Pathway in Broilers. β
Go to Publication β
Frontiers in cell and developmental biology (Front Cell Dev Biol ) Vol: 9 Issue Pages: 616219 Pub: 2021 Epub: 2021 Feb 9 Authors Wang M , Wang B , Wang S , Lu H , Wu H , Ding M , Ying L , Mao Y , Li Y , |
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Effect of Quercetin on Lipids Metabolism Through Modulating the Gut Microbial and AMPK/PPAR Signaling Pathway in Broilers. β
Go to Publication β
Frontiers in cell and developmental biology (Front Cell Dev Biol ) Vol: 9 Issue Pages: 616219 Pub: 2021 Epub: 2021 Feb 9 Authors Wang M , Wang B , Wang S , Lu H , Wu H , Ding M , Ying L , Mao Y , Li Y , |
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Effect of Quercetin on Lipids Metabolism Through Modulating the Gut Microbial and AMPK/PPAR Signaling Pathway in Broilers. β
Go to Publication β
Frontiers in cell and developmental biology (Front Cell Dev Biol ) Vol: 9 Issue Pages: 616219 Pub: 2021 Epub: 2021 Feb 9 Authors Wang M , Wang B , Wang S , Lu H , Wu H , Ding M , Ying L , Mao Y , Li Y , |
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Positive Synergistic Effects of Quercetin and Rice Bran on Human Gut Microbiota Reduces Enterobacteriaceae Family Abundance and Elevates Propionate in a Bioreactor Model. β
Go to Publication β
Frontiers in microbiology (Front Microbiol ) Vol: 12 Issue Pages: 751225 Pub: 2021 Epub: 2021 Sep 30 Authors Ghimire S , Wongkuna S , Sankaranarayanan R , Ryan EP , Bhat GJ , Scaria J , |
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Positive Synergistic Effects of Quercetin and Rice Bran on Human Gut Microbiota Reduces Enterobacteriaceae Family Abundance and Elevates Propionate in a Bioreactor Model. β
Go to Publication β
Frontiers in microbiology (Front Microbiol ) Vol: 12 Issue Pages: 751225 Pub: 2021 Epub: 2021 Sep 30 Authors Ghimire S , Wongkuna S , Sankaranarayanan R , Ryan EP , Bhat GJ , Scaria J , |
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Positive Synergistic Effects of Quercetin and Rice Bran on Human Gut Microbiota Reduces Enterobacteriaceae Family Abundance and Elevates Propionate in a Bioreactor Model. β
Go to Publication β
Frontiers in microbiology (Front Microbiol ) Vol: 12 Issue Pages: 751225 Pub: 2021 Epub: 2021 Sep 30 Authors Ghimire S , Wongkuna S , Sankaranarayanan R , Ryan EP , Bhat GJ , Scaria J , |
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Antitumor Effect and Gut Microbiota Modulation by Quercetin, Luteolin, and Xanthohumol in a Rat Model for Colorectal Cancer Prevention. β
Go to Publication β
Nutrients (Nutrients ) Vol: 16 Issue 8 Pages: Pub: 2024 Apr 13 Epub: 2024 Apr 13 Authors Pérez-Valero Á , Magadán-Corpas P , Ye S , Serna-Diestro J , Sordon S , Huszcza E , Poplonski J , Villar CJ , Lombó F , |
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Antitumor Effect and Gut Microbiota Modulation by Quercetin, Luteolin, and Xanthohumol in a Rat Model for Colorectal Cancer Prevention. β
Go to Publication β
Nutrients (Nutrients ) Vol: 16 Issue 8 Pages: Pub: 2024 Apr 13 Epub: 2024 Apr 13 Authors Pérez-Valero Á , Magadán-Corpas P , Ye S , Serna-Diestro J , Sordon S , Huszcza E , Poplonski J , Villar CJ , Lombó F , |
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Antitumor Effect and Gut Microbiota Modulation by Quercetin, Luteolin, and Xanthohumol in a Rat Model for Colorectal Cancer Prevention. β
Go to Publication β
Nutrients (Nutrients ) Vol: 16 Issue 8 Pages: Pub: 2024 Apr 13 Epub: 2024 Apr 13 Authors Pérez-Valero Á , Magadán-Corpas P , Ye S , Serna-Diestro J , Sordon S , Huszcza E , Poplonski J , Villar CJ , Lombó F , |
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Antitumor Effect and Gut Microbiota Modulation by Quercetin, Luteolin, and Xanthohumol in a Rat Model for Colorectal Cancer Prevention. β
Go to Publication β
Nutrients (Nutrients ) Vol: 16 Issue 8 Pages: Pub: 2024 Apr 13 Epub: 2024 Apr 13 Authors Pérez-Valero Á , Magadán-Corpas P , Ye S , Serna-Diestro J , Sordon S , Huszcza E , Poplonski J , Villar CJ , Lombó F , |
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Antitumor Effect and Gut Microbiota Modulation by Quercetin, Luteolin, and Xanthohumol in a Rat Model for Colorectal Cancer Prevention. β
Go to Publication β
Nutrients (Nutrients ) Vol: 16 Issue 8 Pages: Pub: 2024 Apr 13 Epub: 2024 Apr 13 Authors Pérez-Valero Á , Magadán-Corpas P , Ye S , Serna-Diestro J , Sordon S , Huszcza E , Poplonski J , Villar CJ , Lombó F , |
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Antitumor Effect and Gut Microbiota Modulation by Quercetin, Luteolin, and Xanthohumol in a Rat Model for Colorectal Cancer Prevention. β
Go to Publication β
Nutrients (Nutrients ) Vol: 16 Issue 8 Pages: Pub: 2024 Apr 13 Epub: 2024 Apr 13 Authors Pérez-Valero Á , Magadán-Corpas P , Ye S , Serna-Diestro J , Sordon S , Huszcza E , Poplonski J , Villar CJ , Lombó F , |
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Antitumor Effect and Gut Microbiota Modulation by Quercetin, Luteolin, and Xanthohumol in a Rat Model for Colorectal Cancer Prevention. β
Go to Publication β
Nutrients (Nutrients ) Vol: 16 Issue 8 Pages: Pub: 2024 Apr 13 Epub: 2024 Apr 13 Authors Pérez-Valero Á , Magadán-Corpas P , Ye S , Serna-Diestro J , Sordon S , Huszcza E , Poplonski J , Villar CJ , Lombó F , |
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Antitumor Effect and Gut Microbiota Modulation by Quercetin, Luteolin, and Xanthohumol in a Rat Model for Colorectal Cancer Prevention. β
Go to Publication β
Nutrients (Nutrients ) Vol: 16 Issue 8 Pages: Pub: 2024 Apr 13 Epub: 2024 Apr 13 Authors Pérez-Valero Á , Magadán-Corpas P , Ye S , Serna-Diestro J , Sordon S , Huszcza E , Poplonski J , Villar CJ , Lombó F , |
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Antitumor Effect and Gut Microbiota Modulation by Quercetin, Luteolin, and Xanthohumol in a Rat Model for Colorectal Cancer Prevention. β
Go to Publication β
Nutrients (Nutrients ) Vol: 16 Issue 8 Pages: Pub: 2024 Apr 13 Epub: 2024 Apr 13 Authors Pérez-Valero Á , Magadán-Corpas P , Ye S , Serna-Diestro J , Sordon S , Huszcza E , Poplonski J , Villar CJ , Lombó F , |
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Quercetin modulates the gut microbiota as well as the metabolome in a rat model of osteoarthritis. β
Go to Publication β
Bioengineered (Bioengineered ) Vol: 12 Issue 1 Pages: 6240-6250 Pub: 2021 Dec Epub: Authors Lan H , Hong W , Qian D , Peng F , Li H , Liang C , Du M , Gu J , Mai J , Bai B , Peng G , |
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Quercetin Reduces Inflammation and Protects Gut Microbiota in Broilers. β
Go to Publication β
Molecules (Basel, Switzerland) (Molecules ) Vol: 27 Issue 10 Pages: Pub: 2022 May 19 Epub: 2022 May 19 Authors Sun L , Guo L , Xu G , Li Z , Appiah MO , Yang L , Lu W , |
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Quercetin alleviates intestinal inflammation and improves intestinal functions via modulating gut microbiota composition in LPS-challenged laying hens. β
Go to Publication β
Poultry science (Poult Sci ) Vol: 102 Issue 3 Pages: 102433 Pub: 2023 Mar Epub: 2022 Dec 16 Authors Feng J , Li Z , Ma H , Yue Y , Hao K , Li J , Xiang Y , Min Y , |
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Quercetin alleviates intestinal inflammation and improves intestinal functions via modulating gut microbiota composition in LPS-challenged laying hens. β
Go to Publication β
Poultry science (Poult Sci ) Vol: 102 Issue 3 Pages: 102433 Pub: 2023 Mar Epub: 2022 Dec 16 Authors Feng J , Li Z , Ma H , Yue Y , Hao K , Li J , Xiang Y , Min Y , |
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Quercetin Alleviates Insulin Resistance and Repairs Intestinal Barrier in db/db Mice by Modulating Gut Microbiota. β
Go to Publication β
Nutrients (Nutrients ) Vol: 16 Issue 12 Pages: Pub: 2024 Jun 14 Epub: 2024 Jun 14 Authors Yuan M , Sun T , Zhang Y , Guo C , Wang F , Yao Z , Yu L , |
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Quercetin metabolism by fecal microbiota from healthy elderly human subjects. β
Go to Publication β
PloS one (PLoS One ) Vol: 12 Issue 11 Pages: e0188271 Pub: 2017 Epub: 2017 Nov 27 Authors Tamura M , Hoshi C , Kobori M , Takahashi S , Tomita J , Nishimura M , Nishihira J , |
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Quercetin metabolism by fecal microbiota from healthy elderly human subjects. β
Go to Publication β
PloS one (PLoS One ) Vol: 12 Issue 11 Pages: e0188271 Pub: 2017 Epub: 2017 Nov 27 Authors Tamura M , Hoshi C , Kobori M , Takahashi S , Tomita J , Nishimura M , Nishihira J , |
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Quercetin ameliorates celiac-related intestinal inflammation caused by wheat gluten through modulating oxidative stress, Th1/Th2/Treg balance, and intestinal microflora structure. β
Go to Publication β
Food & function (Food Funct ) Vol: 15 Issue 18 Pages: 9343-9356 Pub: 2024 Sep 16 Epub: 2024 Sep 16 Authors Yu T , Xie Y , Wang Z , Li J , Shen Y , Yuan J , Gao J , Fakruddin M , Wu Y , Chen H , |
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Synergy of Dietary Quercetin and Vitamin E Improves Cecal Microbiota and Its Metabolite Profile in Aged Breeder Hens. β
Go to Publication β
Frontiers in microbiology (Front Microbiol ) Vol: 13 Issue Pages: 851459 Pub: 2022 Epub: 2022 May 17 Authors Amevor FK , Cui Z , Du X , Feng J , Shu G , Ning Z , Xu D , Deng X , Song W , Wu Y , Cao X , Wei S , He J , Kong F , Du X , Tian Y , Karikari B , Li D , Wang Y , Zhang Y , Zhu Q , Zhao X , |
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Synergy of Dietary Quercetin and Vitamin E Improves Cecal Microbiota and Its Metabolite Profile in Aged Breeder Hens. β
Go to Publication β
Frontiers in microbiology (Front Microbiol ) Vol: 13 Issue Pages: 851459 Pub: 2022 Epub: 2022 May 17 Authors Amevor FK , Cui Z , Du X , Feng J , Shu G , Ning Z , Xu D , Deng X , Song W , Wu Y , Cao X , Wei S , He J , Kong F , Du X , Tian Y , Karikari B , Li D , Wang Y , Zhang Y , Zhu Q , Zhao X , |
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Synergy of Dietary Quercetin and Vitamin E Improves Cecal Microbiota and Its Metabolite Profile in Aged Breeder Hens. β
Go to Publication β
Frontiers in microbiology (Front Microbiol ) Vol: 13 Issue Pages: 851459 Pub: 2022 Epub: 2022 May 17 Authors Amevor FK , Cui Z , Du X , Feng J , Shu G , Ning Z , Xu D , Deng X , Song W , Wu Y , Cao X , Wei S , He J , Kong F , Du X , Tian Y , Karikari B , Li D , Wang Y , Zhang Y , Zhu Q , Zhao X , |
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Synergy of Dietary Quercetin and Vitamin E Improves Cecal Microbiota and Its Metabolite Profile in Aged Breeder Hens. β
Go to Publication β
Frontiers in microbiology (Front Microbiol ) Vol: 13 Issue Pages: 851459 Pub: 2022 Epub: 2022 May 17 Authors Amevor FK , Cui Z , Du X , Feng J , Shu G , Ning Z , Xu D , Deng X , Song W , Wu Y , Cao X , Wei S , He J , Kong F , Du X , Tian Y , Karikari B , Li D , Wang Y , Zhang Y , Zhu Q , Zhao X , |
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Synergy of Dietary Quercetin and Vitamin E Improves Cecal Microbiota and Its Metabolite Profile in Aged Breeder Hens. β
Go to Publication β
Frontiers in microbiology (Front Microbiol ) Vol: 13 Issue Pages: 851459 Pub: 2022 Epub: 2022 May 17 Authors Amevor FK , Cui Z , Du X , Feng J , Shu G , Ning Z , Xu D , Deng X , Song W , Wu Y , Cao X , Wei S , He J , Kong F , Du X , Tian Y , Karikari B , Li D , Wang Y , Zhang Y , Zhu Q , Zhao X , |
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Synergy of Dietary Quercetin and Vitamin E Improves Cecal Microbiota and Its Metabolite Profile in Aged Breeder Hens. β
Go to Publication β
Frontiers in microbiology (Front Microbiol ) Vol: 13 Issue Pages: 851459 Pub: 2022 Epub: 2022 May 17 Authors Amevor FK , Cui Z , Du X , Feng J , Shu G , Ning Z , Xu D , Deng X , Song W , Wu Y , Cao X , Wei S , He J , Kong F , Du X , Tian Y , Karikari B , Li D , Wang Y , Zhang Y , Zhu Q , Zhao X , |
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Synergy of Dietary Quercetin and Vitamin E Improves Cecal Microbiota and Its Metabolite Profile in Aged Breeder Hens. β
Go to Publication β
Frontiers in microbiology (Front Microbiol ) Vol: 13 Issue Pages: 851459 Pub: 2022 Epub: 2022 May 17 Authors Amevor FK , Cui Z , Du X , Feng J , Shu G , Ning Z , Xu D , Deng X , Song W , Wu Y , Cao X , Wei S , He J , Kong F , Du X , Tian Y , Karikari B , Li D , Wang Y , Zhang Y , Zhu Q , Zhao X , |
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Synergy of Dietary Quercetin and Vitamin E Improves Cecal Microbiota and Its Metabolite Profile in Aged Breeder Hens. β
Go to Publication β
Frontiers in microbiology (Front Microbiol ) Vol: 13 Issue Pages: 851459 Pub: 2022 Epub: 2022 May 17 Authors Amevor FK , Cui Z , Du X , Feng J , Shu G , Ning Z , Xu D , Deng X , Song W , Wu Y , Cao X , Wei S , He J , Kong F , Du X , Tian Y , Karikari B , Li D , Wang Y , Zhang Y , Zhu Q , Zhao X , |
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Quercetin inhibits NTHi-triggered CXCR4 activation through suppressing IKKa/NF-?B and MAPK signaling pathways in otitis media. β
Go to Publication β
International journal of molecular medicine (Int J Mol Med ) Vol: 42 Issue 1 Pages: 248-258 Pub: 2018 Jul Epub: 2018 Mar 20 Authors Ma YK , Chen YB , Li P , |
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Allium cepa L. and Quercetin Inhibit RANKL/Porphyromonas gingivalis LPS-Induced Osteoclastogenesis by Downregulating NF-?B Signaling Pathway. β
Go to Publication β
Evidence-based complementary and alternative medicine : eCAM (Evid Based Complement Alternat Med ) Vol: 2015 Issue Pages: 704781 Pub: 2015 Epub: 2015 Jul 26 Authors Oliveira T , Figueiredo CA , Brito C , Stavroullakis A , Ferreira AC , Nogueira-Filho G , Prakki A , |
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Allium cepa L. and Quercetin Inhibit RANKL/Porphyromonas gingivalis LPS-Induced Osteoclastogenesis by Downregulating NF-?B Signaling Pathway. β
Go to Publication β
Evidence-based complementary and alternative medicine : eCAM (Evid Based Complement Alternat Med ) Vol: 2015 Issue Pages: 704781 Pub: 2015 Epub: 2015 Jul 26 Authors Oliveira T , Figueiredo CA , Brito C , Stavroullakis A , Ferreira AC , Nogueira-Filho G , Prakki A , |
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Reshaping faecal gut microbiota composition by the intake of trans-resveratrol and quercetin in high-fat sucrose diet-fed rats. β
Go to Publication β
The Journal of nutritional biochemistry (J Nutr Biochem ) Vol: 26 Issue 6 Pages: 651-60 Pub: 2015 Jun Epub: 2015 Feb 26 Authors Etxeberria U , Arias N , Boqué N , Macarulla MT , Portillo MP , Martínez JA , Milagro FI , |
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Reshaping faecal gut microbiota composition by the intake of trans-resveratrol and quercetin in high-fat sucrose diet-fed rats. β
Go to Publication β
The Journal of nutritional biochemistry (J Nutr Biochem ) Vol: 26 Issue 6 Pages: 651-60 Pub: 2015 Jun Epub: 2015 Feb 26 Authors Etxeberria U , Arias N , Boqué N , Macarulla MT , Portillo MP , Martínez JA , Milagro FI , |
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Quercetin in a lotus leaves extract may be responsible for antibacterial activity. β
Go to Publication β
Archives of pharmacal research (Arch Pharm Res ) Vol: 31 Issue 5 Pages: 640-4 Pub: 2008 May Epub: 2008 May 15 Authors Li M , Xu Z , |
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Quercetin in a lotus leaves extract may be responsible for antibacterial activity. β
Go to Publication β
Archives of pharmacal research (Arch Pharm Res ) Vol: 31 Issue 5 Pages: 640-4 Pub: 2008 May Epub: 2008 May 15 Authors Li M , Xu Z , |
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Quercetin in a lotus leaves extract may be responsible for antibacterial activity. β
Go to Publication β
Archives of pharmacal research (Arch Pharm Res ) Vol: 31 Issue 5 Pages: 640-4 Pub: 2008 May Epub: 2008 May 15 Authors Li M , Xu Z , |
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Quercetin in a lotus leaves extract may be responsible for antibacterial activity. β
Go to Publication β
Archives of pharmacal research (Arch Pharm Res ) Vol: 31 Issue 5 Pages: 640-4 Pub: 2008 May Epub: 2008 May 15 Authors Li M , Xu Z , |
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Quercetin in a lotus leaves extract may be responsible for antibacterial activity. β
Go to Publication β
Archives of pharmacal research (Arch Pharm Res ) Vol: 31 Issue 5 Pages: 640-4 Pub: 2008 May Epub: 2008 May 15 Authors Li M , Xu Z , |
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Quercetin Increases Growth Performance and Decreases Incidence of Diarrhea and Mechanism of Action in Weaned Piglets. β
Go to Publication β
Oxidative medicine and cellular longevity (Oxid Med Cell Longev ) Vol: 2024 Issue Pages: 5632260 Pub: 2024 Epub: 2024 Aug 6 Authors Mao Y , Yang Q , Liu J , Fu Y , Zhou S , Liu J , Ying L , Li Y , |
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Quercetin Increases Growth Performance and Decreases Incidence of Diarrhea and Mechanism of Action in Weaned Piglets. β
Go to Publication β
Oxidative medicine and cellular longevity (Oxid Med Cell Longev ) Vol: 2024 Issue Pages: 5632260 Pub: 2024 Epub: 2024 Aug 6 Authors Mao Y , Yang Q , Liu J , Fu Y , Zhou S , Liu J , Ying L , Li Y , |
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Quercetin Increases Growth Performance and Decreases Incidence of Diarrhea and Mechanism of Action in Weaned Piglets. β
Go to Publication β
Oxidative medicine and cellular longevity (Oxid Med Cell Longev ) Vol: 2024 Issue Pages: 5632260 Pub: 2024 Epub: 2024 Aug 6 Authors Mao Y , Yang Q , Liu J , Fu Y , Zhou S , Liu J , Ying L , Li Y , |
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Quercetin Increases Growth Performance and Decreases Incidence of Diarrhea and Mechanism of Action in Weaned Piglets. β
Go to Publication β
Oxidative medicine and cellular longevity (Oxid Med Cell Longev ) Vol: 2024 Issue Pages: 5632260 Pub: 2024 Epub: 2024 Aug 6 Authors Mao Y , Yang Q , Liu J , Fu Y , Zhou S , Liu J , Ying L , Li Y , |
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Quercetin hybrid-hydrogel microparticles modulate gut microbiota and improve memory in an antibiotic-induced dysbiosis rat model. β
Go to Publication β
Scientific reports (Sci Rep ) Vol: 15 Issue 1 Pages: 42429 Pub: 2025 Nov 25 Epub: 2025 Nov 25 Authors Parappilly SJ , Vasu DA , Krishnan KAA , Yadukrishnan MB , Mohan MC , Pradeep M , Deepti A , Aneesa PA , Krishnakumar IM , Chakrapani PSB , |
All suggestions are computed solely on their predicted microbiome impact. Safety, side-effects etc must be evaluated by your medical professionals before starting. Some items suggests have significant risk of adverse consequences for some people.
Special thanks to David F Morrison and Geert Van Houcke for doing Quality Assurance. Special thanks to Oliver Luk, B.Sc. (Biology) from BiomeSight for spot checking the coding of data from the US National Library of Medicine
This is an Academic site. It generates theoretical models of what may benefit a specific microbiome results.
Copyright 2016-2023 Lassesen Consulting, LLC [2007], DBA, Microbiome Prescription. All rights served.
Permission to data scrap or reverse engineer is explicitly denied to all users. U.S. Code Title 18 PART I CHAPTER 47 Β§β―1030, CETS No.185, CFAA
Use of data on this site is prohibited except under written license. There is no charge for individual personal use. Use for any commercial applications or research requires a written license.
Caveat emptor: Analysis and suggestions are based on modelling (and thus infererence) based on studies. The data sources are usually given for those that wish to consider alternative inferences. theories and models.
Inventions/Methodologies on this site are Patent Pending.
Microbiome Prescription do not make any representations that data or analyses available on this site is suitable for human diagnostic purposes, for informing treatment decisions, or for any other purposes and accept no responsibility or liability whatsoever for such use.
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